Didn't feel anything strange: Scientists told about a woman, in whose body they found 18 mutations of coronavirus

47-a summer woman from St. Petersburg got infected in the hospital from a roommate, passed 17 tests and was ill for six months

Случай 47-летней петербурженки – первый исследованный в России.

Russian scientists described an amazing case - in the body of a 47-year-old woman it developed immediately 18 mutations of the coronavirus SARS-CoV-2. The news instantly "blew up" the Internet and became the basis for many apocalyptic theories and predictions. Which one is true, and what not, and what this discovery really means for science and for ordinary people - says "Komsomolskaya Pravda" in St. Petersburg ".

Study, chained in the morning 12 January attention of the largest Russian media, carried out by several scientific organizations at once - Skolkovo Scientific and Technical Institute, Institute for Information Transmission Problems RAS, First Saint Petersburg State Medical University named after Pavlov and - as a leading - Research Institute of Influenza named after A. A. Смородинцева.

Woman, which became his main "object", came to the attention of scientists by accident - during selective monitoring of patients with coronavirus infection. According to "Komsomolskaya Pravda", patient 47 years, she is from St. Petersburg and suffers from Hodgkin's lymphoma, an oncological disease, in which the lymph nodes are affected.

 

Не ощущала ничего странного: Ученые рассказали о женщине, в организме которой нашли 18 мутаций коронавируса

According to scientists, a woman contracted a coronavirus, when I was in the hospital.

FROM 27 March to 17 April the woman was in the hospital, received scheduled chemotherapy, – рассказывает исполняющий обязанности директора НИИ гриппа Дмитрий Лиознов. - And around the same period she contracted the coronavirus from her roommate.

By the end of April, the patient developed subfebrile (i.e, not higher 38 degrees) temperature. PCR test, which she did, turned out to be positive. Then the weirdness began: from May to July, the woman made four more tests. They all tested negative., despite, that the symptoms of COVID-19 have not disappeared and even worsened. Finally, the fifth test was positive again - as were the next seven.

In total, the Petersburg woman made 17 тестов и проболела почти полгода

только в сентябре ее анализы на коронавирус стали стабильно отрицательными. And when scientists from the Research Institute of Influenza compared the genomes of viruses, received from the patient at different periods, they were in for a great surprise - in the woman's body, in more than five months, developed 18 mutations SARS-CoV-2.

And one of them was like two peas in a pod resembled a mutation, found in the so-called "British" strain. And two more - coincided with the strain, because of which at the end of last year in Denmark announced a total "sweep" of minks.

But wait get scared.

According to the authors of the study themselves, nothing terrible follows from their discovery. End of the world, announced by some media, canceled - once again.

 

Не ощущала ничего странного: Ученые рассказали о женщине, в организме которой нашли 18 мутаций коронавируса

According to the study authors, этот случай – первый описанный, but, probably, by no means the only one. Just a virus for that, to start accumulating mutations, usually not enough time.

Any virus, not excluding SARS-CoV-2

Попав в организм человека, is changing, – объясняет Дмитрий Лиознов. - This is absolutely normal.. It's just that in most cases the virus remains in the body for a very short time - as a rule, no more than two weeks without developing mutations. Here because, that the woman's immune system was initially weakened, him, probably, managed to "linger" and eventually get such a large number of mutations.

Wherein, specifies the expert, no fundamental differences from the existing strains, this new (his, by the way, have already christened the "Russian") does not have. I.e, he did not become more dangerous in the process of mutation - which means, expect some unpleasant surprises from him, likely, not worth it.

By the way, even the patient herself, from which this very strain was eventually "isolated", did not feel any strange symptoms - the standard course of the disease, no more. By the way, к настоящему дню она благополучно вылечилась и чувствует себя хорошо – насколько, anyway, allows her chronic illness.

Не ощущала ничего странного: Ученые рассказали о женщине, в организме которой нашли 18 мутаций коронавируса

В организме женщины развился в том числе зловещий “британский штамм”, due to which any communication with England was previously closed.

Этот случай формирования мутаций у больных с ослабленным иммунитетом.

Данная находка имеет значение для науки – поможет изучить, how the virus is changing, каким законам и стратегиям подчиняются эти изменения, and how they can affect the course of the disease and the effectiveness of vaccines.

As for the "British" and "Danish" strains, which developed in the body of a Petersburg woman, nor to Britain, has never traveled to Denmark in recent months - most likely, это просто наиболее выгодная вирусу стратегия развития. However, it is too early to draw any far-reaching conclusions in this matter - the study of the phenomenon is still in full swing.


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